Skip Navigation



European Journal of Echocardiography Advance Access published online on January 20, 2009
European Journal of Echocardiography, doi:10.1093/ejechocard/jen333
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
10/4/532    most recent
jen333v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Schoen, S. P.
Right arrow Articles by Strasser, R. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Schoen, S. P.
Right arrow Articles by Strasser, R. H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

Nomograms for severity of aortic valve stenosis using peak aortic valve pressure gradient and left ventricular ejection fraction

Steffen P. Schoen*, Till F. Zimmermann, Charlotte Rosenberger, Gesa Elmer, Dirk Stolte, Carsten Wunderlich and Ruth H. Strasser

Department of Cardiology and Intensive Care, Heart Center, University of Technology, Dresden, Fetscherstr. 76, 01307 Dresden, Germany

Received 8 October 2008; accepted after revision 21 December 2008.

* Corresponding author. Tel: +49 351 4501701, Fax: +49 351 4501702, Email: cardiology{at}email.de


  Abstract

Aims: Continuity equation to evaluate aortic valve area (AVACE) is critically dependent on accurate measurement of left ventricular outflow tract diameter and velocity. To circumvent these limitations, the present study aimed to generate nomograms for a facilitated estimation of aortic valve area using peak aortic valve pressure gradient ({Delta}pAv) and left ventricular ejection fraction (LVEF).

Methods and results: Two hundred and fifty-five subjects with non-invasively and invasively defined aortic valve stenosis (AS) formed the basis of this study. Basis of the nomograms was the correlation analysis between {Delta}pAv and AVA as estimated by AVACE within different LVEF groups. LVEF differed from 65.6 ± 1.8% (Group I, LVEF > 60%) to 34.5 ± 4.3% (Group IV, LVEF ≥ 30%). {Delta}pAv and AVA varied from 85.6 ± 19.5 mmHg and 0.69 ± 0.16 cm2 in Group I to 58.5 ± 15.9 mmHg and 0.73 ± 0.23 cm2 in Group IV ({Delta}pAv: P < 0.001). Mean AVACE showed no significant difference between the groups. Correlation between {Delta}pAv and AVACE was statistically significant with P < 0.001 in all subgroups (R2 between 0.72 and 0.76). Furthermore, a prospective estimation of AVA using the developed nomograms correlated very well with invasively determined AS using the Gorlin formula (R2 = 0.76, SEE = 0.21 cm2, bias 0.04 cm2).

Conclusion: The present study has established and confirmed a solid, easy to use nomogram-based method to accurately quantify severe AS.

Keywords: Aortic valve stenosis; Continuity equation; Nomogram


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Eur J EchocardiogrHome page
M. Uzun, A. Kirilmaz, M. Yokusoglu, O. Yiginer, and C. Genc
Which is more useful nomogram or equation?
Eur J Echocardiogr, November 9, 2009; (2009) jep163v1.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.