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European Journal of Echocardiography Advance Access published online on May 29, 2008

European Journal of Echocardiography, doi:10.1093/ejechocard/jen164
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Primary cardiac angiosarcoma evaluated with contrast two-dimensional and real-time three-dimensional echocardiography

Hyun Suk Yang, Shantanu Sengupta, Matt M. Umland, Krishnaswamy Chandrasekaran and Farouk Mookadam*

Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Mayo Clinic Arizona, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA

Received 6 February 2008; accepted after revision 12 April 2008.

* Corresponding author. Tel: +1 480 301 6907; fax: +1 480 301 8018. E-mail address: mookadam.farouk{at}mayo.edu


   Abstract

A 63-year-old lady presented with syncope and atypical chest pain. Conventional two-dimensional (2D) contrast echocardiogram showed a highly vascular mass compressing the right atrium without direct communication. A real-time three-dimensional echocardiogram (RT3DE) revealed its outer spatial relationship with the surrounding structures and its inner heterogeneity as well. A chest computed tomography revealed a solid cardiac mass (6  x  7 cm2) arising from the right atrium and multiple pulmonary nodules. Histopathology of the pericardial fluid confirmed angiosarcoma. To our knowledge, this is the first report of histology-confirmed primary cardiac angiosarcoma, which was completely evaluated by conventional 2D, contrast, and RT3DE.

Keywords: Angiosarcoma; Contrast echocardiography; Three-dimensional echocardiography


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