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European Journal of Echocardiography Advance Access published online on October 2, 2007
European Journal of Echocardiography, doi:10.1016/j.euje.2007.08.005
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Reproducibility of tissue Doppler parameters of asynchrony in patients with advanced LV dysfunction{star}

Eva Mandysová*, Tomás Mráz, Milos Táborsky and Petr Niederle

Department of Cardiology, Hospital Na Homolce, Roentgenova 2, 150 30 Prague 5, Czech Republic

Received 27 December 2006; accepted after revision 15 August 2007.

* Corresponding author. Tel: +420257272204; fax: +4202572 73297. E-mail address: eva.mandysova{at}homolka.cz (E. Mandysová).


  Abstract

Aims: To assess the reproducibility of tissue Doppler myocardial velocities in patients with dilated ventricles and markedly reduced systolic function (ejection fraction <35%).

Methods and results: Forty-one patients referred for cardiac resynchronization therapy (CRT) were evaluated using tissue Doppler echocardiography. The inter and intra-individual reproducibility of peak systolic myocardial velocities and the intra-ventricular delay in three apical projections was assessed by repeated evaluation of each registered data set. Variability (measured by the coefficient of variation) ranged between 18 and 56% for the peak systolic velocities and between 32 and 117% for the time intervals.

Conclusion: The reproducibility of the tissue Doppler echocardiography parameters (peak systolic myocardial velocity and intra-ventricular delay) was poor in our set of patients with dilated left ventricles and low ejection fraction. The most probable causes of our poor results are discussed including the missing standardization of the TDI measurements.

Keywords: Tissue Doppler echocardiography; Myocardial velocity; Reproducibility of measurement; Cardiac resynchronization therapy; Heart failure

{star} Statistical calculations were performed by Jakub Hrkal from the Institute of Health Information and Statistics of the Czech Republic using Stata v. 8.


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