Copyright © 2007, The European Society of Cardiology
Response to the letter to the editor
Department of Cardiology, Thoraxcenter, Erasmus MC, s-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
Received 21 July 2007; .
* Corresponding author. Tel.: +31 10 4635994; fax: +31 10 4635498. o.soliman@erasmusmc.nl f.j.tencate@erasmusmc.nl
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We thank Dr. Saura for the interest in our work. Dr. Saura raised an important issue regarding the preferred venous route of contrast administration during bubble studies for assessment of a patent foramen ovale (PFO). In the vast majority of published literature and more relevant in clinical practice an antecubital venous