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European Journal of Echocardiography 2007 8(5):332-440; doi:10.1016/j.euje.2006.06.005
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Copyright © 2006, The European Society of Cardiology

Restrictive mitral inflow pattern is a strong independent predictor of lack of viable myocardium after a first acute myocardial infarction

Augusto Sestilia,*, Claudio Colettaa, Valerio Mannob, Silvia Pernaa, Marco Renzia, Patrizia Romanoa, Roberto Riccia and Vincenzo Cecia

aDivision of Cardiology, Santo Spirito Hospital, Lungotevere in Sassia 1, Rome, Italy
bIstituto Superiore di Sanità, Rome, Italy

Received 4 December 2005; received in revised form 17 May 2006; accepted after revision 2 June 2006.

sestil{at}libero.it

* Corresponding author. Via Pitide, 34-00124 Roma, Italy. Tel.: +39 06 50914714, fax: +39 06 68352458.


  Abstract

In patients with acute myocardial infarction (AMI) a restrictive mitral inflow pattern successfully predicts clinical outcome. The impact of myocardial viability on the mitral inflow velocities, however, is unknown. One hundred and forty-one patients with a first AMI underwent two-dimensional, Doppler and dobutamine stress echocardiography (DSE). Patients were classified into two groups based on Doppler measurement of left ventricular filling: a restrictive group (18 patients), and a non-restrictive group (123 patients).

In the non-restrictive group, myocardial viability at DSE was found in 56 patients, while in the restrictive group only three patients showed contractile reserve (46% vs. 16%, p<0.03). The multivariate logistic regression analysis demonstrated that restrictive mitral inflow pattern was a strong independent predictor of lack of viable myocardium (OR=12.45, p<0.001).

Keywords: Echocardiography; Diastole; Viable myocardium


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