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European Journal of Echocardiography Advance Access originally published online on January 30, 2009
European Journal of Echocardiography 2009 10(3):471-472; doi:10.1093/ejechocard/jep003
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org.

Calcified right ventricular thrombus and antiphospholipid syndrome

Jose Alberto de Agustín*, Iván Javier Nuñez-Gil, Borja Ruiz-Mateos, Maria del Carmen Manzano, David Vivas, Leopoldo Pérez de Isla, Jose Zamorano and Carlos Macaya

Cardiovascular Institute, San Carlos University Hospital, C/Profesor Martin Lagos s/n, 28040 Madrid, Spain

Received 23 November 2008; accepted after revision 11 January 2009; online publish-ahead-of-print 30 January 2009.

* Corresponding author. Tel: +34 696228197; fax: +34 915649716. E-mail address: albertutor{at}hotmail.com


  Abstract

Antiphospholipid syndrome has been associated with venous and arterial thrombotic events but intracardiac thrombosis is rare. We describe a case about a 30-year-old woman, admitted with a 6-month history of arthralgia, fatigue, and intermittent fever. Subsequent investigation revealed the presence of a large and calcified mass in the right ventricular outflow tract attached to the subvalvular tricuspid apparatus. Cardiac surgery was performed and histological examination demonstrated it to be composed entirely of calcified thrombus. Screening laboratory evaluation for hypercoagulable states confirmed the diagnosis of antiphospholipid syndrome.

Keywords: Ventricular thrombus; Antiphospholipid syndrome


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