European Journal of Echocardiography 2008 9(1):74-75; doi:10.1016/j.euje.2006.12.010
Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2007. For permissions please email: journals.permissions@oxfordjournals.org.
Quadricuspid aortic valve
Ali Reza Moaref and
Amir Aslani*
Cardiology Department, Shiraz University of Medical Sciences, Shiraz, Iran
Received 6 December 2006; accepted after revision 27 December 2006; online publish-ahead-of-print 9 March 2007.
* Corresponding author. Cardiology Department, Namazee Hospital, Shiraz, Iran (PO Box 71935-1334). Tel: +98 917 3156216; fax: +98 711 6279733. E-mail address: draslani{at}yahoo.com
Keywords: Quadricuspid aortic valve; Aortic regurgitation
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Illustration
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A 57-year-old woman presented with a history of dyspnea on exertion
since 4 months prior to admission. She denied chest pain. Her
medical history was not significant. Physical examination revealed
wide pulse pressure and arterial hypertension (170/65 mmHg).
A diastolic murmur of grade 4/6 was heard at the left sternal
border. ECG displayed sinus rhythm with evidence of left ventricular
enlargement. Chest x-ray showed cardiomegaly. Review of previous
trans-thoracic echocardiography of the patient, which was done
6 months earlier, revealed only moderate aortic regurgitation.
Another echocardiography was done that revealed severe aortic
regurgitation and normal appearing aortic valve. The patient
underwent trans-esophageal echocardiography for detailed echocardiographic
examination of the aortic valve and root. Interestingly, trans-esophageal
echocardiography showed a quadricuspid aortic valve with poor
coaptation of aortic leaflets (
Figure 1A–C) (see
Movie Clip 1). Also, severe aortic regurgitation was detected (
Figure 1D) (see
Movie Clip 2). Quadricuspid aortic valve is a rare
congenital heart defect and has been an incidental finding at
open heart surgery or at autopsy.
1 Hurwitz
et al.2 introduced
a classification nomenclature for quadricuspid aortic valve
that included seven different types named A to G.

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Figure 1 Trans-esophageal echocardiography of a patient presenting with a history of dyspnea on exertion for 4 months prior to admission. A quadricuspid aortic valve with poor aortic leaflets coaptation is seen (A–C). Severe aortic regurgitation is also seen (D).
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Supplementary material
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Supplementary material associated with this article can be found in the online version.
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References
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- Tutarel O. The quadricuspid aortic valve: a comprehensive review. J Heart Valve Dis (2004) 13:534–7.[Web of Science][Medline]
- Hurwitz LE, Roberts WC. Quadricuspid semilunar valve. Am J Cardiol (1973) 31:623–6.[CrossRef][Web of Science][Medline]

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