European Journal of Echocardiography 2006 7(5):405-406; doi:10.1016/j.euje.2006.02.010
Copyright © 2006, The European Society of Cardiology
MRSA endocarditis – Postcardiac surgery
Andrew James Wiper*,
Matthias Schmitt,
Ian Schofield and
David H. Roberts
Blackpool Victoria Hospital, Cardiology, Whinney Heys Road, Blackpool, Lancashire FY3 8NR, UK
Received 4 December 2005; received in revised form 12 February 2006; accepted after revision 28 February 2006.
* Tel.: +44 01772 866005. a_wiper{at}yahoo.com
Keywords: MRSA; Endocarditis; Cardiac surgery
An 80-year-old lady presented with a history of pyrexia and rigors two months following a ventricular aneurysmectomy with patch repair. Blood cultures demonstrated methicillin-resistant Staphylococcus aureus (EMRSA15). A transthoracic echocardiography performed on admission showed a large vegetation on the inferior wall of the aneurysm patch (Fig. 1). She was initially treated with intravenous vancomycin (1g BD) according to the sensitivity of the organism. Five days later, the vegetation had become more heterogeneous with an abscess cavity behind the vegetation (Fig. 2). Rethoracotomy was considered to be of too high a risk. Following clinical deterioration her medication was changed to intravenous teicoplanin (400mg od) and rifampicin (300mg qds), and a total of eight weeks intravenous therapy was followed by nine months of oral monotherapy with rifampicin (300mg od). At 1 month there was an infero-basal septal abscess with no identifiable vegetation (Fig. 3). At 9 months there was no evidence of endocarditis, and a small infero-basal septal aneurysm persisted (Fig. 4), with no identifiable left to right shunt. Learning point: recent studies suggest that MRSA endocarditis is becoming more prevalent and is associated with a persistent bacteremia.1 This case highlights the value of long-term oral antibiotic therapy.
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Reference
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- Jung Yoon Hee, Yong Choi Jun, Oh Kim Chang, Myung Kim June, Goo Song Young. A comparison of clinical features and mortality among methicillin-resistant and methicillin-sensitive strains of staphylococcus aureus endocarditis. Yonsei Medical Journal (2005) 46(4):496–502.[Web of Science][Medline]

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