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European Journal of Echocardiography 2006 7(3):247-249; doi:10.1016/j.euje.2005.04.013
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Copyright © 2005, The European Society of Cardiology

Echocardiographic images in mitral valve repair by "edge to edge" technique

U. Da Col, G. Bardelli, I. Di Bella*, G. Minniti and T. Ragni

Divisione di Cardiochirurgia, Ospedale Silvestrini, S. Andrea delle Fratte, Perugia 06100, Italy

Received 24 September 2004; received in revised form 14 April 2005; accepted after revision 20 April 2005.

* Corresponding author. Tel.: +39 75 5782300; fax: +39 75 5782214. isidorodibella{at}yahoo.it


    Abstract
 Top
 Abstract
 Introduction
 Case report
 Discussion
 References
 
The "edge to edge" or "double orifice" technique is a new surgical option of mitral repair when functional valve insufficiency is present, due to ischemic or dilated cardiomyopathy. This technique is not frequently used and radically changes mitral anatomy and hemodynamic. Therefore, echocardiographic examination is completely different and implies good experience to evaluate postoperative valve function. For these reasons we present a case report of a patient who underwent this repair and was evaluated in the follow up by standard transthoracic echocardiography: the anatomical and functional assessment that was satisfactory compared with transesophageal examination is documented.

Keywords: Mitral insufficiency; Mitral valve repair; Echocardiography


    Introduction
 Top
 Abstract
 Introduction
 Case report
 Discussion
 References
 
Functional mitral insufficiency due to ischemic heart disease or dilated cardiomyopathy is an increasingly important cause of mitral regurgitation with poor long term prognosis. An effective but non-frequent surgical correction is the "edge to edge" or "double orifice" technique described by Alfieri and colleagues1,2 and the intraoperative evaluation is done by transesophageal echocardiography. Nevertheless, postoperative and follow up assessment of these patients is very important and in this case report we evaluated the effectiveness of transthoracic approach.


    Case report
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 Abstract
 Introduction
 Case report
 Discussion
 References
 
A 78-year-old man with a history of non-Q wave inferior myocardial infarction followed by moderate dyspnea on exertion is presented. The symptoms had been present for one year and recently worsened. The physical examination revealed a moderate systolic murmur on the apex which radiated to the left axilla. Transthoracic echocardiography showed good global left ventricular function with impaired inferior wall motion. The mitral valve showed normal leaflets and severe regurgitation with the jet directed towards the atrial septum. Transesophageal echocardiography showed a moderately dilated mitral annulus (35mm antero-posterior diameter), posterior leaflet prolapse and severe regurgitation.3 Coronary angiography revealed a subocclusive lesion on the posterolateral branch of the circumflex coronary artery. He underwent surgical mitral repair connecting the midportion of the anterior and posterior leaflets ("edge to edge") and stabilizing the annulus with a complete flexible annuloplasty ring Sovering N° 30 (Sorin Biomedica, Saluggia, Italy). The postoperative course was uneventful and the patient was discharged on day 7.

Transthoracic echocardiography was performed before discharge. In parasternal short axis and apical four chamber view the double mitral valve orifices was seen as an "eight shaped" image during diastole (Figs. 1–3GoGo) with two separate antegrade flows. We consider a good result of the "edge to edge" technique when the residual mitral regurgitation is not more than 1+/4+ and the residual total mitral area is greater than 2.5cm2. Therefore, it is important to obtain the mitral area by the planimetry of the two orifices (Fig. 4). This area must be similar to the area of the two orifices calculated by Doppler technique. The posteromedial orifice mean velocity was 1.30m/s, mean gradient 7.6mmHg, PHT 155ms and the functional area 1.42cm2. The anterolateral orifice mean velocity was 1.25m/s, mean gradient 6.9mmHg, PHT 186ms and functional area 1.18cm2. In this patient the total functional area was 2.6cm2 which can be considered trivial mitral stenosis. In the same view, the annuloplasty ring appears as a hyperechogenic structure along the annular circumference. In the different projections the point of systolic leaflets coaptation is in the same plane as the valve annulus.


Figure 1
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Figure 1 Parasternal short axis view shows the double mitral orifice as an "eight shaped" image during diastole (LA, left atrium; LV, left ventricle; RV, right ventricle).

 


Figure 2
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Figure 2 Parasternal short axis view shows two diastolic transmitral flow jets completely separated just below the valve plane.

 


Figure 3
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Figure 3 Four chamber apical view showing the diastolic transmitral flow separated with two different jets.

 


Figure 4
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Figure 4 Parasternal short axis view shows the planimetered area of the two orifices of the mitral valve.

 

    Discussion
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 Abstract
 Introduction
 Case report
 Discussion
 References
 
Similar to more commonly used mitral repair procedures, the "edge to edge" or "double orifice" procedure allows a good and stable leaflets coaptation even in ischemic mitral regurgitation. Since functional regurgitation appears to result from an imbalance between the opening and closing forces acting on the mitral leaflets, suturing the two leaflets together to ensure coaptation is a simple solution to a complex problem. The annuloplasty increases and stabilizes the surface of coaptation of the leaflets while the Alfieri technique prevents the possible development of leaflet tethering and repair failure in the follow up of these ischemic patients.4 For this reason, and for the presence of leaflet prolapse, both procedures were used. Postoperative assessment of the patients after standard repair techniques can be performed by transthoracic echocardiography and transesophageal echocardiography should be limited to selected cases. The "edge to edge" mitral repair is a recently introduced surgical option, used in selected cases and that completely changes the anatomy and hemodynamic of the valve.5 Echocardiographic experience for postoperative assessment remains limited.6 This case shows that transthoracic echocardiography is an effective technique for assessing the anatomical and functional results in early and long term follow up.


    References
 Top
 Abstract
 Introduction
 Case report
 Discussion
 References
 

  1. Maisano F., Schreuder J.J., Oppizzi M., Fiorani B., Fino C., Alfieri O. The double-orifice technique as a standardized approach to treat mitral regurgitation due to severe myxomatous disease: surgical technique. Eur J Cardiothorac Surg (2000) 17:201–205.[Abstract/Free Full Text]
  2. Alfieri O., Maisano F., De Bonis M., Stefano P.L., Torracca L., Oppizzi M., et al. The double-orifice technique in mitral valve repair: a simple solution for complex problems. J Thorac Cardiovasc Surg (2001) 122:674–681.[Abstract/Free Full Text]
  3. Jouan J., Tapia M., Cook R.C., Lansac E., Acar C. Ischemic mitral valve prolapse: mechanisms and implications for valve repair. Eur J Cardiothorac Surg (2004) 26:1112–1117.[Abstract/Free Full Text]
  4. Matsunaga A., Tahta S.A., Duran C.M.G. Failure of reduction annuloplasty for functional ischemic mitral regurgitation. J Heart Valve Dis (2004) 13(3):390–397.[Web of Science][Medline]
  5. Maisano F., Redaelli A., Pennati G., Fumero R., Torraca L., Alfieri O. The hemodynamic effects of double orifice valve repair for mitral regurgitation: a 3D computational model. Eur J Cardiothorac Surg (1999) 15:419–425.[Abstract/Free Full Text]
  6. Kinnaird T.D., Bradley L.M., Ignaszewski A.P., Abel J.G., Thompson C.R. Edge-to-edge repair for functional mitral regurgitation: an echocardiographic study of hemodynamic consequences. J Heart Valve Dis (2003) 12:280–286.[Web of Science][Medline]

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