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European Journal of Echocardiography Advance Access published online on June 20, 2008

European Journal of Echocardiography, doi:10.1093/ejechocard/jen182
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Hamartomas of mature cardiac myocytes

Shaji C. Menon1,*, Dylan V. Miller2, Allison K. Cabalka1 and Donald J. Hagler1

1 Pediatric Cardiology, Mayo Clinic, 200 First Street SW, Gonda 6, Rochester, MN 55905, USA
2 Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA

Received 1 March 2008; accepted after revision 25 May 2008.

* Corresponding author. Tel: +1 507 284 3297; fax: +1 507 284 3968. E-mail address: menon.shaji{at}mayo.edu


   Abstract

We present two paediatric cases of a very rare, pathologically benign, and primary cardiac tumour composed of mature cardiac myocytes with disorganized cytoarchitecture called hamartoma of mature cardiac myocyte. The patients are usually asymptomatic, may have non-specific electrocardiogram findings, and rarely have associated sudden death. The clinical presentation and pathological and imaging findings of this rare tumour are discussed. Cardiac magnetic resonance imaging may help differentiate this tumour from other common differential diagnosis like cardiac fibroma and hypertrophic cardiomyopathy.

Keywords: Cardiac hamartoma; Paediatric; Imaging


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