European Journal of Echocardiography Advance Access published online on April 19, 2008
European Journal of Echocardiography, doi:10.1093/ejechocard/jen148
Assessment of early diastolic left ventricular function by two-dimensional echocardiographic speckle tracking
Cardiac Services, Level 6, Flinders Medical Centre, Flinders Drive, Bedford Park, SA 5042, Australia
Received 23 December 2007; .
* Corresponding author. Tel: +61 882046075; fax: +61 882044907.E-mail address: rebecca.perry{at}fmc.sa.gov.au
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Abstract |
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Aims: To determine whether the degree of untwisting of the apex in early diastole is related to established parameters of diastolic function.
Methods and results: Data from 71 hospital inpatients with preserved left ventricular systolic function who underwent standard two-dimensional echocardiography was analysed using an off-line speckle tracking software package. Early diastolic mitral inflow velocity (e), mitral septal annular tissue Doppler velocity (e'), and the rate of early diastolic apical untwist in degrees per second (rotR) from a parasternal short-axis view of the apex were all measured. Of the 71 patients, 14 had normal diastolic function, 25 had an abnormal relaxation pattern, 27 had a pseudonormalized pattern, and 5 had a restrictive pattern as defined by standard echocardiography criteria. Both e' and the ratio of e:e' correlated with the rate (speed) of early diastolic apical untwist (rotR) (P < 0.001 for both).
Conclusion: This non-invasive assessment of apical diastolic untwist is related to established echocardiographic measures of diastolic function and may illustrate the importance of a ventricular suction effect in varying left ventricular filling states.
Keywords: Echocardiography; Speckle tracking; Diastolic function