European Journal of Echocardiography Advance Access originally published online on March 20, 2008
European Journal of Echocardiography 2008 9(4):555-559; doi:10.1093/ejechocard/jen120
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Aortic valve closure: relation to tissue velocities by Doppler and speckle tracking in normal subjects
1 Department of Circulation and Medical Imaging, NTNU, ISB Medisinsk Teknisk Forskningssenter, NO-7489 Trondheim, Norway
2 Department of Cardiology, St Olav Hospital, Trondheim, Norway
Received 5 July 2007; accepted after revision 14 October 2007; online publish-ahead-of-print 20 March 2008.
* Corresponding author. Tel: +47 73 55 04 19; fax: +47 73 59 86 13. E-mail address: sveinaaa{at}ntnu.no
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Aims: The aim of this study is to resolve what event in velocity/time curves represents aortic valve closure (AVC) by comparing the timing of AVC visually seen in high frame rate B-mode images with simultaneously recorded apical tissue Doppler imaging (TDI) and speckle-tracking-based velocity/time curves from normal subjects.
Methods and results: A total of 73 recordings from 11 normal subjects were analysed. The acquisition frame rate was equal for both TDI and B-mode (mean 147.5 FPS). The study shows conclusively that the initial negative velocity spike at end-systole occurs before AVC, 26.7 ± 6.2 ms before reference (P < 0.001). The event closest to the reference was the time point of zero velocity after the negative spike, 2.6 ± 8.2 ms before reference. These events are related to the reference in the same way for velocity/time curves by speckle tracking, colour M-mode, and pulsed wave tissue Doppler.
Conclusions: AVC in velocity/time curves should be positioned at the end of the negative spike after ejection. Establishing AVC from the correct event in velocity/time curves will ensure more consistent displacement, velocity, strain, and strain rate parameters.
Keywords: Heart; Echocardiography; End systole; Systolic time interval
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