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European Journal of Echocardiography Advance Access originally published online on February 26, 2007
European Journal of Echocardiography 2008 9(3):388-390; doi:10.1016/j.euje.2006.12.006
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2007. For permissions please email: journals.permissions@oxfordjournals.org

Complete regression of massive cardiac involvement associated with acute T cell leukemia following chemotheraphy

Nurcan Arat1,*, Sule Mine Bakanay2, Emrah Yildiz1, Omac Tufekcioglu1 and Zehra Golbasi1

1 Turkiye Yuksek Ihtisas Hospital, Department of Cardiology, Ankara, Turkey
2 Ankara University, Faculty of Medicine, Department of Hematology, Ankara, Turkey

Received 6 November 2006; accepted after revision 15 December 2006; online publish-ahead-of-print 26 February 2007.

* Corresponding author. Tel: +90 312 3061129; fax: +90 312 362 4502. E-mail address: aratnurcan{at}gmail.com (N. Arat).


  Abstract

Adult T cell leukemia/lymphomas are aggressive disorders, which infiltrate not only the bone marrow but extensively the visceral organs as well. A case with left ventricular systolic dysfunction with myocardial infiltration and massive pericardial effusion which was demonstrated with echocardiography is discussed. The patient responded well to pericardial drainage and subsequent chemotherapy. The dramatic improvement in echocardiographic findings after chemotherapy gave a clue to investigate suspected patients with aggressive leukemia and lymphomas for exclusion of leukemic infiltration of myocardium.

Keywords: Adult T cell leukemia/lymphomas; Echocardiography; Pericardial effusion; Left ventricular dysfunction


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