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European Journal of Echocardiography 2007 8(6):463-469; doi:10.1016/j.euje.2006.08.002
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Copyright © 2007, The European Society of Cardiology

Application of tissue Doppler to interpretation of exercise echocardiography: Diagnostics of ischemia localization in patients with ischemic heart disease

Angela Zagatina*, Nadezhda Zhuravskaya and Anna Kotelnikova

Almazov Research Institute of Cardiology, 15, Parkhomenko Street, 194156 Saint-Petersburg, Russia

Received 24 April 2006; received in revised form 29 June 2006; accepted after revision 11 August 2006.

* Corresponding author. Tel.: +7 8123798472. zag_angel{at}yahoo.com


   Abstract

Development of optimal methods for the objective non-invasive diagnosis of coronary artery disease remains a challenge for imaging techniques in stress tests.

Aim: The aim of this study was to obtain quantitative diagnostic criteria TDI which could detect significant coronary artery disease during exercise echocardiography.

Methods and results: We evaluated regional systolic and diastolic myocardial functions of 123 patients by pulsed wave tissue Doppler imaging (TDI) in eight segments of left ventricle during exercise stress testing. Diagnostic criteria were obtained by comparing TDI and coronary angiography data. Best cut-points of velocity parameters allowed developing two diagnostic models for the detection of left anterior descending (LAD) and circumflex (LCx) artery diseases. The accuracy of the TDI diagnostic model for LAD-disease was 86.2% and for LCx-disease 78.3%. There were no criteria for the detection of RCA disease in this study.

Conclusion: So TDI is a very accurate method for the detection of LAD- and LCx-disease during exercise stress echocardiography.

Keywords: Tissue Doppler imaging; Exercise echocardiography; Quantitative stress echocardiography


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