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European Journal of Echocardiography 2007 8(6):431-437; doi:10.1016/j.euje.2007.03.002
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Copyright © 2007, The European Society of Cardiology

Automated coupled-contour and robust myocardium tracking in stress echocardiography

Stefanos E. Karagiannisa, Jos Roelandta, Maleeha Qazib, Sriram Krishnanb, Harm H.H. Feringaa, Radosav Vidakovica, George Karatasakisc, Dennis V. Cokkinosc and Don Poldermansa,*

aDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands
bSiemens Medical Solutions, Malvern, PA, USA
c1st Department of Cardiology, Onassis Cardiac Surgery Centre, Athens, Greece

Received 5 August 2006; received in revised form 3 October 2006; accepted after revision 4 March 2007.

* Corresponding author. Department of Cardiology, Room H 921, Erasmus MC, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands. Tel.: +31104639222; fax: +31104634957. d.poldermans{at}erasmusmc.nl


  Abstract

Dobutamine stress echocardiography is a commonly used imaging modality for the diagnosis of coronary artery disease and the detection of myocardial viability. The major limitations are that it is operator dependent and that the analysis is subjective and qualitative resulting in interobserver variability. It is also tedious and time consuming. Consequently, several quantitative approaches have been proposed, such as acoustic quantification and color kinesis but none of these has proved to be fully quantitative. In this manuscript we describe the development of a new, quantitative technique based on tracking of both endocardium and epicardium providing information of endocardial excursion and myocardial thickening, a crucial parameter of wall function evaluation. Preliminary data indicate that the method is practical and feasible, but clinical trials are required to prove whether it will improve the sensitivity and specificity of dobutamine stress echocardiography.

Keywords: Dobutamine stress echocardiography; Subjective; Quantitative techniques; Myocardial thickening


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