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European Journal of Echocardiography 2007 8(5):309-316; doi:10.1016/j.euje.2006.12.005
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Copyright © 2007, The European Society of Cardiology

Tissue Doppler Imaging in the assessment of selection and response from cardiac resynchronization therapy

Antonio Vitarellia,*, Pasquale Franciosaa and Salvatore Rosaniob

aCardiac Department, "La Sapienza" University, Via Lima 35, 00198 Rome, Italy
bCardiac Department, The University of Texas, Galveston, TX, USA

Received 25 October 2006; received in revised form 29 November 2006; accepted after revision 15 December 2006.

vitar{at}tiscali.it

* Corresponding author. Tel.: +39 6 8530 1427; fax: +39 6 884 1926.


  Abstract

Mechanistic studies, observational evaluations, and randomized trials have consistently demonstrated the beneficial effects of cardiac resynchronization therapy (CRT) in patients with moderate-to-severe chronic systolic heart failure and ventricular dyssynchrony who have failed optimal medical treatment. However, despite the promising results, in some patients undergoing CRT, the symptoms of heart failure do not improve or even worse. One of the most important reasons for this failure is probably the lack of distinct mechanical dyssynchrony before implantation. This review discusses the actual and potential role of Tissue Doppler Imaging in selection of patients and optimisation of CRT.

Keywords: Heart failure; Resynchronization therapy; Echocardiography; Tissue Doppler Imaging


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