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European Journal of Echocardiography 2007 8(2):151-154; doi:10.1016/j.euje.2005.12.010
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Copyright © 2005, The European Society of Cardiology

Platypnoea orthodeoxia in a patient with aortic root dilatation and a patent foramen ovale

James Pembertona,*, Timothy Irvinea, Michael J. Stewartb, George Antunesc and G. John Gibsond

aDepartment of Cardiology, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK
bDepartment of Cardiology, James Cook University Hospital, Middlesbrough, UK
cDepartment of Chest Medicine, James Cook University Hospital, Middlesbrough, UK
dDepartment of Respiratory Medicine, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK

Received 1 September 2005; received in revised form 29 November 2005; accepted after revision 15 December 2005.

* Corresponding author. Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK. Tel.: +44 191 233 6161. james.pemberton{at}ncl.ac.uk


   Abstract

Platypnoea orthodeoxia syndrome is a rare condition in which shortness of breath and hypoxaemia occur when upright and resolve when prone. The hypoxaemia results from increased right to left shunting of deoxygenated blood, when standing, through a patent foramen ovale (PFO), atrial septal defect (ASD) or other right to left shunt, in the absence of raised right-heart pressure. We present the case of a patient with platypnoea orthodeoxia with marked shunting through a large PFO, evaluated by transesophageal and transthoracic echo.

Keywords: Platypnoea orthodeoxia; Patent foramen ovale


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