Copyright © 2005, The European Society of Cardiology
Global and regional left ventricular function assessment with 16-detector row CT: Comparison with echocardiography and cardiovascular magnetic resonance
aDepartment of Cardiology, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands
bDepartment of Radiology, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands
cInteruniversity Cardiology Institute of the Netherlands, P.O. Box 19258, 3501 DG Utrecht, The Netherlands
Received 21 April 2005; received in revised form 18 June 2005; accepted after revision 7 July 2005.
* Corresponding author. Tel.: +31 715262020; fax: +31 715266809. jbax{at}knoware.nl
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Abstract |
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Aims To compare multidetector row computed tomography (MDCT) global and regional left ventricular (LV) function assessment with echocardiography and cardiovascular magnetic resonance (CMR).
Methods and results In 25 patients, who were referred for noninvasive angiography with 16-detector row CT, LV function assessment was also performed. A subsequent echocardiogram was performed, and in a subgroup of patients, CMR examination was completed to evaluate LV function. For global function assessment, the LV ejection fraction (LVEF) was calculated. Regional LV function was scored using a 17-segment model and a 4-point scoring system.
MDCT agreed well with echocardiography for the assessment of LVEF (r=0.96; bias 0.54%; p<0.0001) and regional LV function (
=0.78). Eight patients had no contra-indications and gave informed consent for CMR examination. A fair correlation between MDCT and CMR was demonstrated in the assessment of LVEF (r=0.86; bias –1.5%; p<0.01). Regional LV function agreement between MDCT and CMR was good (=0.86).
Conclusion MDCT agreed well with both echocardiography and CMR in the assessment of global and regional LV function. Global and regional LV function may accurately be evaluated by 16-detector row CT, and can be added to a routine CT image analysis protocol without need for additional contrast or imaging time.
Keywords: Left ventricular function; MDCT; Echocardiography; CMR
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