Copyright © 2005, The European Society of Cardiology
Functional diagnosis of coronary stenosis using tissue tracking provides best sensitivity and specificity for left circumflex disease: experience from the MYDISE (myocardial Doppler in stress echocardiography) study
on behalf of the MYDISE investigators
aDepartment of Clinical Physiology, Karolinska University Hospital, Huddinge, SE-141 86 Stockholm, Sweden
bWales Heart Research Institute, University of Wales College of Medicine, Cardiff, UK
Received 12 March 2004; received in revised form 7 July 2004; accepted after revision 9 July 2004.
* Corresponding author. Tel.: +46 8 5858 7226; fax: +46 8 774 8082. samir.saha{at}labmed.ki.se samir.saha{at}kus.se
 |
Abstract |
|---|
Aims To evaluate the diagnostic capacity of quantitative analysis of segmental longitudinal myocardial displacement images (tissue tracking, TT) during dobutamine stress echocardiography for the detection of patients with coronary artery disease (CAD).
Methods and results TT-generated colour-coded maps of systolic segmental longitudinal displacement were obtained by post-processing of echocardiographic data from 105 patients with CAD and 90 low risk individuals selected from MYDISE database. Quantitative analysis of the distribution pattern of segmental displacement during dobutamine stress was most successful when a ratio of basal (high amplitude) to apical (low amplitude) colour-coded displacement bands (B/A ratio) was employed. Applied in four different left ventricular sectors, the B/A ratio provided a significant discrimination of patients with CAD (p<0.05 in the anterior and p<0.001 in the inferior wall) as assessed by receiver operating characteristic analysis. The procedure was most sensitive when applied in inferior wall for the detection of left circumflex coronary artery disease, the B/A ratio of 0.8 giving the best combination of sensitivity (77±8%) and specificity (77±5%) values.
Conclusion Quantification of dobutamine stress echocardiography using TT is an efficient diagnostic approach and a valuable additional modality in functional cardiac imaging for the initial identification of patients suspected for CAD.
Keywords: Coronary artery disease; Tissue Doppler; Dobutamine stress echocardiography; Tissue tracking
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  R.A. Argyle and S.G. Ray Stress and strain: double trouble or useful tool? Eur J Echocardiogr, August 1, 2009; 10(6): 716 - 722. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. R. Larsen, P. Torp, K. Norrild, and E. Sloth Propofol reduces tissue-Doppler markers of left ventricle function: a transthoracic echocardiographic study Br. J. Anaesth., February 1, 2007; 98(2): 183 - 188. [Abstract] [Full Text] [PDF]
|
|