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European Journal of Echocardiography 2004 5(5):386-390; doi:10.1016/j.euje.2004.02.006
© 2004 by European Society of Cardiology
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Copyright © 2004, The European Society of Cardiology

Reversal of cardiac abnormalities in a young man with idiopathic hypereosinophilic syndrome using a tyrosine kinase inhibitor

Luigi Ascionea,*, Mario De Micheleb, Maria Accadiaa, Pasquale Spadaroa, Salvatore Rumoloa and Bernardino Tuccilloa

aDivision of Cardiology, S. Maria di Loreto Hospital, Viale dei Pini 4, 80055 Portici, Naples, Italy
bDivision of Cardiology, Moscati Hospital, Aversa, Italy

Received 4 November 2003; received in revised form 19 February 2004; accepted after revision 24 February 2004.

* Corresponding author. Tel./fax: +39-081-7755064. luigi.ascione20{at}tin.it


  Abstract

We report a case of idiopathic hypereosinophilic syndrome in a young man, who showed symptoms and electrocardiographic findings mimicking an acute coronary syndrome. Two-dimensional echocardiography, together with laboratory data, allowed us to make the diagnosis and to start a treatment with imatinib mesylate, a 2-phenylamonopyrimidine-based tyrosine kinase inhibitor, which reversed the cardiac abnormalities.

Keywords: Echocardiography; Hypereosinophilic syndrome


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