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European Journal of Echocardiography 2004 5(5):335-346; doi:10.1016/j.euje.2003.12.003
© 2004 by European Society of Cardiology
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Copyright © 2004, The European Society of Cardiology

Factor analysis of the left ventricle by echocardiography (FALVE): a new tool for detecting regional wall motion abnormalities

Frédérique Frouina, Annie Delouchea, Hanna Raffoulb, Hervé Dieboldb, Eric Abergelb and Benoît Diebolda,b,*

aINSERM U494, CHU Pitié-Salpêtrière, Paris, France
bService d'Echocardiographie, Hôpital Européen Georges Pompidou, Paris, France

Received 31 July 2003; received in revised form 17 December 2003; accepted after revision 22 December 2003.

* Corresponding author. Service d'Echocardiographie, Hôpital Européen Georges Pompidou, 20 Rue Leblanc, 75015 Paris, France. Tel.: +33-1-56-09-38-04; fax: +33-1-56-09-38-10. benoit.diebold{at}egp.ap-hop-paris.fr


   Abstract

Background: Factor analysis of the left ventricle in echography was developed to study the regional wall motion. Two factors and associated factor images were estimated using specific constraints: one "constant" factor and another "contraction–relaxation" factor. The constant factor was encoded in green, the positive component of the contraction in red and the negative in blue.

Methods: The evaluation was carried out on 12 patients with LBBB or pacemaker (group A), and on 26 others (group B). The segments were graded separately on the cine-loops by three experienced echocardiographers. Similarly, the three-color combination of the factor images was read at the endocardial border and each segment was scored.

Results: An absolute concordance was obtained for 64.8% of the segments and a relative concordance (within one grade) for 97.2%. They were 71% and 99.6% in group B. Most of the discordant cases were explained by the global motion during the cardiac cycle. The standard deviation of the difference between the mean wall motion scores was 0.38 for all the patients; it was reduced to 0.30 in group B.

Conclusion: Factor analysis is a promising tool to study the regional wall motion. It might become useful for assessing segmental wall motion in 2D and 3D echo.

Keywords: Segmental wall motion; Echocardiography; Image sequence; Factor analysis


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