© 2004 by European Society of Cardiology
Copyright © 2003, The European Society of Cardiology
Identifying patients without favourable long-term outcome among those with medically stabilized unstable angina and a negative dipyridamole stress echocardiogram
Instituto Cardiovascular, Hospital Clínico San Carlos, Martín Lagos, s/n, 28040 Madrid, Spain
Received 1 September 2003; received in revised form 21 November 2003; accepted after revision 28 November 2003.
* Corresponding author. Tel.: +34-91-330-32-90; fax: +34-91-330-32-91. raulmorenog{at}terra.es
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Abstract |
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Aims: Patients with medically stabilized unstable angina and a negative stress echocardiogram have a favourable outcome as a whole. This study sought to identify which subsets of patients are associated with serious events at long-term within this population.
Methods and results: We studied and followed-up 128 patients (mean 2.2 ± 1.3 years) with medically stabilized unstable angina and a negative dipyridamole stress echocardiogram. Cumulative survival rates were 98.2±1.3%, 96.0±2.2% and 93.2±3.2%, at 1, 2 and 4 years, respectively. Freedom from events (death, myocardial infarction, and revascularization) were 98.2±1.3%, 96.0±2.2% and 86.3±6.0%, at 1, 2, and 4 years, respectively. Cumulative mortality rate was higher in men (3.6±2.5%, 8.5±4.1%, and 12.2±5.4% at 1, 2, and 4 years, vs. 0% at the end of the follow-up in women; p = 0.034), and in those with previous myocardial infarction (4.3±4.3%, 9.1±6.2%, and 18.2±2.3% at 1, 2 and 4 years, vs. 1.1±1.1%, 2.9±2.1%, and 2.9±2.1% in those without previous myocardial infarction, respectively; p = 0.047).
Conclusion: Among patients with medically stabilized unstable angina and a negative dipyridamole stress echocardiogram, male gender and previous myocardial infarction are associated with a non-favourable outcome.
Keywords: DSE; Dipyridamole stress echocardiogram; ECG; Electrocardiography; UA; Unstable angina
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