Skip Navigation

European Journal of Echocardiography 2004 5(3):182-188; doi:10.1016/S1525-2167(03)00078-7
© 2004 by European Society of Cardiology
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Barros, M.V.L
Right arrow Articles by da Costa Rocha, M.O
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Barros, M.V.L
Right arrow Articles by da Costa Rocha, M.O
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Copyright © 2003, The European Society of Cardiology

Diastolic function in Chagas' disease: An echo and tissue Doppler imaging study

M.V.L Barrosa,b,*, F.S Machadoa, A.L.P Ribeiroa,b,c and M.O da Costa Rochab,c

aEcoar-Noninvasive Diagnostic Medicine, Brazil
bPost-Graduation Course in Tropical Medicine-UFMG (Federal University of Minas Gerais), Brazil
cDepartment of Internal Medicine-UFMG (Federal University of Minas Gerais), Brazil

Received 20 March 2003; received in revised form 22 July 2003; accepted after revision 25 July 2003.

* Corresponding author. Avenida do Contorno 6760, Santo Antônio, 30110-110 Belo Horizonte, MG — Brazil. Tel./fax: +55-21-312277833. ecoar{at}gold.com.br


  Abstract

Aims: With the purpose of studying left ventricular filling in Chagas' disease (Chd), we evaluated 169 patients with Chd using echocardiography and Doppler and tissue Doppler imaging (TDI).

Methods and results: The patients were divided into four groups according to the pattern of left ventricular filling: Group 0—normal filling pattern, Group 1—abnormal relaxation, Group 2—pseudonormal flow pattern, and Group 3—restrictive pattern. All patients were submitted to TDI of the basal portion of the left ventricle's walls. Diastolic dysfunction was found in 21.3% of the patients, with a strong correlation between the worsening of diastolic function and ejection fraction (r = 0.78, p<0.001). TDI septal e' wave measurement was the best method for the detection of any kind of diastolic dysfunction. Considering a cut-off point of 11 cm/s, a reduced e' wave value has 97% sensitivity, 84% specificity, 62% positive predictive value, and 99% negative predictive value. The septal E/e' ratio was the best index for the detection of advanced diastolic dysfunction. Considering a cut-point of 7.2, an elevated E/e' ratio has 100% sensitivity, 88% specificity, 54.2% positive predictive value, and 100% negative predictive value.

Conclusion: This study showed the characterization of the various patterns of left ventricle diastolic function by echocardiography and Doppler in Chagas' disease and the usefulness of TDI in the assessment of diagnosis of diastolic dysfunction in this disease.

Keywords: Chagas' disease; tissue Doppler imaging; diastolic function


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.