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European Journal of Echocardiography 2003 4(4):320-326; doi:10.1016/S1525-2167(02)00172-5
© 2003 by European Society of Cardiology
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Copyright © 2003, The European Society of Cardiology

Assessment of Regional Myocardial Hypoperfusion with Myocardial Contrast Echocardiography Using Intravenous Bolus Application in Patients with Acute Chest Pain: A Double Case Report

A Hagendorff1,*, A Goeckritz1, A Neugebauer1, T Rother1, T Linke2, D Pfeiffer1 and H Becher3

1Department of Cardiology–Angiology, University of Leipzig, Leipzig, Germany
2Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany
3Department of Cardiology, University of Oxford, Oxford, UK

Received 21 August 2002; accepted after revision 5 December 2002.

* Address for correspondence: Andreas Hagendorff, Department of Cardiology–Angiology, University of Leipzig, Johannisallee 32, 04103 Leipzig, Germany. Tel: +49-341-97-12650; Fax: +49-341-97-12659. hages{at}medizin.uni-leipzig.de


  Abstract

Myocardial contrast echocardiography using power Doppler harmonic imaging is able to document myocardial hypoperfusion. Two case reports demonstrate the potential of intravenous bolus application of microbubbles in patients with acute chest pain due to myocardial ischaemia to detect regional low flow conditions. The case reports will focus on the necessity to present Doppler intensity kinetics by Doppler intensity vs time plots or coloured M-modes to present the data more objectively. In addition, the hypoperfusion detected with myocardial contrast echocardiography via bolus injection of microbubbles can only be proven by changes of regional perfusion between repetitive myocardial contrast echocardiography measurements or by additional perfusion analysis, e.g. by scintiscanning.

Keywords: power Doppler harmonic imaging; myocardial contrast echocardiography; contrast agent; myocardial perfusion; bolus injection


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A Hagendorff, A Werner, D Pfeiffer, and H Becher
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