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European Journal of Echocardiography Advance Access originally published online on September 12, 2009
European Journal of Echocardiography 2009 10(8):984-986; doi:10.1093/ejechocard/jep105
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

Tissue Doppler imaging and contrast-enhanced cardiac magnetic resonance in primary cardiac amyloidosis

J.-P. Smedema1,* and R. James2

1 Netcare Blaauwberg Hospital, Room 2A7, Waterville Crescent, Sunningdale 7441, Cape Town, Republic of South Africa
2 Dr Davies Pathologists, 26 Thor Circle, Viking Business Place, Thornton 7450, Republic of South Africa

Received 28 February 2009; accepted after revision 14 August 2009; online publish-ahead-of-print 12 September 2009.

* Corresponding author: Tel: +21 554 3731; fax: +21 554 3741. E-mail address: jansmedema{at}hotmail.com


  Abstract

A 64-year-old female presented with biventricular heart failure. Echocardiography revealed features suggestive of amyloidosis, including segmental impairment of longitudinal strain (rate) in the septal and anterior segments, which matched delayed gadolinium-enhanced cardiac magnetic resonance. Guided endomyocardial biopsy confirmed the presence of perivascular amyloid deposits. Tissue Doppler and gadolinium-enhanced magnetic resonance may be helpful in delineating cardiac amyloidosis.

Keywords: Amyloidosis; Restrictive cardiomyopathy; Heart failure; Tissue Doppler Imaging; Cardiac magnetic resonance


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